Immunomodulatory Therapies Research
Research focused on developing and characterizing new treatments for inflammatory disease.
Immune Modulation in Inflammatory Disease
(Coming November 2023)
All-trans retinoic acid-loaded microparticles were developed and characterized to locally modulate T cells in autoimmune arthritis.
Liposomal Delivery of Gut-Derived Immune Modulator
Liposomal formulations of the short chain fatty acid butyrate were formulated and their effects on T cell function were assessed.
Cyclodextrin-Encapsulated Regulatory T cell Inducer
Rapamycin was encapsulated in cyclodextrins to improve solubility and tested as a DMSO-free alternative to enhance regulatory T cell purity in cell manufacturing.
Immune Response Enhancing Biomaterial Scaffolds
(Coming November 2023)
Cryogel Vaccine Formulation to Enhance Vaccine Efficacy
Multiple injectable cryogel vaccine formulations were synthesized and tested to determine optimal formulation and dosing to enhance immune response.
Implantable Scaffolds for Post-Bone Marrow Transplant Neutrophil Regeneration
Biodegradable injectable cryogel scaffolds were developed to expedite immune reconstitution following bone marrow transplant.